Table 4 RE²-AIM implementation secondary outcomes

Implementation Outcome

Measurement

Level

Reach

# of total patients that the CDS activated on / # of total eligible TBI patients

Patient – Level

Effectiveness

• VTE and Bleeding Event Rates (unadjusted and adjusted)

Patient—Level

• Transfusion Requirements (unadjusted and adjusted)

• Mortality (unadjusted and adjusted)

Equity

• Number of patients that receive adherence across demographic groups (race, ethnic, sex, and age)

Patient – Level

• Effectiveness outcomes (VTE, bleeding event rate, and mortality) across demographic groups

Adoption

Implementation

Number of patients that received adherence with the CPG per site or provider/ number of eligible patients per site or provider

Hospital, Provider-Level

- All-or-none by implementation site

- All-or-none by trauma provider

- Adoption at hospital level by risk level (low, medium, high)

Fidelity to the CPG:

Patient—Level

• Appropriate agent used (e.g. enoxaparin, unfractionated heparin)

• Appropriate dose delivered

• Dose delivered at appropriate time after admission

CDS provider training proficiency by implementation site

CDS order bundle utilization by implementation site

CDS IT integration time (in hours)

Maintenance

• Percent of patients that received the CPG at 6 months post implementation

Patient / Provider Level

• Provider adoption 6 months post implementation

• Average provider score on guideline proficiency quiz (compared to baseline)